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{"type":"standard","title":"4-PhPr-2,5-DMA","displaytitle":"4-PhPr-2,5-DMA","namespace":{"id":0,"text":""},"wikibase_item":"Q133278697","titles":{"canonical":"4-PhPr-2,5-DMA","normalized":"4-PhPr-2,5-DMA","display":"4-PhPr-2,5-DMA"},"pageid":79347635,"thumbnail":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/f/f8/4-PhPr-2%2C5-DMA.svg/330px-4-PhPr-2%2C5-DMA.svg.png","width":320,"height":157},"originalimage":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/f/f8/4-PhPr-2%2C5-DMA.svg/765px-4-PhPr-2%2C5-DMA.svg.png","width":765,"height":375},"lang":"en","dir":"ltr","revision":"1292594560","tid":"4c6ff601-3b3b-11f0-adbd-1db528d3b6e3","timestamp":"2025-05-27T20:43:52Z","description":"Pharmaceutical compound","description_source":"local","content_urls":{"desktop":{"page":"https://en.wikipedia.org/wiki/4-PhPr-2%2C5-DMA","revisions":"https://en.wikipedia.org/wiki/4-PhPr-2%2C5-DMA?action=history","edit":"https://en.wikipedia.org/wiki/4-PhPr-2%2C5-DMA?action=edit","talk":"https://en.wikipedia.org/wiki/Talk:4-PhPr-2%2C5-DMA"},"mobile":{"page":"https://en.m.wikipedia.org/wiki/4-PhPr-2%2C5-DMA","revisions":"https://en.m.wikipedia.org/wiki/Special:History/4-PhPr-2%2C5-DMA","edit":"https://en.m.wikipedia.org/wiki/4-PhPr-2%2C5-DMA?action=edit","talk":"https://en.m.wikipedia.org/wiki/Talk:4-PhPr-2%2C5-DMA"}},"extract":"4-(3-Phenylpropyl)-2,5-dimethoxyamphetamine, also known as 4-PhPr-2,5-DMA, is a serotonin receptor modulator of the phenethylamine, amphetamine, and DOx families. It shows high affinity for both the serotonin 5-HT2A and 5-HT2C receptors and acts as a weak partial agonist or antagonist of the serotonin 5-HT2A receptor. The drug has lower affinity for the serotonin 5-HT2A receptor than its closely related positional isomer 4-PhPr-3,5-DMA. This is an apparent reversal of the usual situation with DOx and related drugs in which the 2,5-dimethoxy pattern is optimal for serotonin 5-HT2A receptor interactions.","extract_html":"
4-(3-Phenylpropyl)-2,5-dimethoxyamphetamine, also known as 4-PhPr-2,5-DMA, is a serotonin receptor modulator of the phenethylamine, amphetamine, and DOx families. It shows high affinity for both the serotonin 5-HT2A and 5-HT2C receptors and acts as a weak partial agonist or antagonist of the serotonin 5-HT2A receptor. The drug has lower affinity for the serotonin 5-HT2A receptor than its closely related positional isomer 4-PhPr-3,5-DMA. This is an apparent reversal of the usual situation with DOx and related drugs in which the 2,5-dimethoxy pattern is optimal for serotonin 5-HT2A receptor interactions.
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